Seattle Regenerative Medicine and Prolotherapy

Your Chronic Pain Specialist

Prolotherapy (Proliferative Therapy) is a Regenerative Medicine treatment for Chronic Pain and a safe and effective alternative to surgery.

Prolotherapy at it’s essence is a non-surgical Regenerative Joint Injection for Ligament, Tendon and Cartilage Reconstruction. It is a recognized orthopedic procedure in medicine since the 1940s (and it’s roots go back to Hippocrates descriptions of sclerotherapy around 400 B.C.) that stimulates the body’s healing processes to strengthen and repair injured and painful joints and connective tissue.

to restore the original strength to the tissue. 

How does Prolotherapy work? 

Prolotherapy’s mechanism is centered around the fact that when ligaments or tendons (connective tissue) are stretched or torn, the joint they are holding destabilizes and involves nerve tissue becoming painful. Prolotherapy, has a unique ability to directly address the cause of the instability, can truly repair the weakened sites and produce new collagen tissue, resulting in lasting permanent stabilization of the joint. Once the joint is stabilized, pain usually resolves completely with adequate treatment.

Prolotherapy works by introducing an irritant, traditionally 5% dextrose solution, into the joint or connective tissue surrounding the pain joint or body region (i.e. – low back, neck, or knee joint). The injection increases growth of new, normal ligament or tendon fibers or cartilage inside the joints. This results in a tightening of the weakened structure. Additional treatments repeat this process, which allows a gradual buildup of tissue to restore the original strength to the tissue. 

What’s in the solution that is injected?

Prolotherapy injections traditionally contain natural substances that stimulate the body’s innate healing ability to treat Chronic Pain conditions. Traditional formulas include dextrose, saline, sarapin, and procaine. More recently in the last 20-30 years or so, Platelet Rich Plasma (PRP) has been used as a solution to inject into joints and into connective tissue outside joints. also, autologous adult (from the same person) and amniotic & placental stem cells have been used to regenerate cartilage in arthritic joints as well as repair tendons, ligaments, and other connective tissue injuries and degenerative joint conditions.

Is the Prolotherapy treatment painful? 

The pain level involved with Prolotherapy will vary according to the structure or joint treated, and the skill of the physician administering the prolotherapy treatment. The procedure can result in increased localized swelling and pain that diminishes quickly. If absolutely needed Tylenol can be used to help with pain from the treatments, however ibuprofen and aspirin must be avoided since they suppress the desired inflammatory healing cascade that helps build, regenerate, and grow new tissue healthy. 

What can Prolotherapy Treat?  

  • Low back pain
  • Neck pain
  • Hip Pain
  • Knee pain
  • Osteoarthritis
  • Elbow pain including golfer’s elbow or tennis elbow
  • Foot pain (including plantar fasciitis, ankle pain or hypermobility)
  • IT Band Syndrome
  • Piriformis Syndrome
  • Temporal Mandibular Joint Syndrome (TMJ)

Please do not ice or use NSAIDS before or after the procedure for maximum benefit. This will interfere with the treatment working.

What is Perineural Injection Therapy? 

Perineural Injection Therapy is a type of Prolotherapy addressing the nerves and fascia using dextrose solution. It aids in treating and resolving stubborn neuropathic conditions and nerve entrapment conditions such as carpal tunnel syndrome, sciantica, and peripheral neuropathies that typically present with burning or tingling pain that comes and goes and is chronic.

Functional Medicine is best combined with Regenerative Medicine for optimal health and benefits. For this reason for optimal benefit from Prolotherapy treatments for this reason it is recommened that you sign up for a program before starting Prolotherapy Treatments.

You must pre-qualify for all Prolotherapy treatments. Not everyone is a cadidate for this medicine. 

Prolotherapy Pricing

Important NOTE: Patients in Lite, Essentials, or Advanced Programs without any contraindications are eligable for Prolotherapy after 4-6 weeks or treatment and detoxification.

Cost for Prolotherapy, Platelet Rich Plasma, Stem Cell Therapy

Area treated – Cost per Treatment
Prolotherapy – Low Back $650
Prolotherapy – Mid Back $650
Prolotherapy – Neck $650
Prolotherapy – Knee, Shoulder, or Hip (each) $500
Prolotherapy – TMJ (each) $350
Prolotherapy – Wrist, Ankle, or Elbow (each) $500
Prolotherapy – Pubis, or Iscial tuberosity $450
Prolotherapy – Foot or Achilles (each) $400
Prolotherapy – Heel or Hand (each) $350
Prolotherapy – Toe(s) or Finger(s) (dependent upon the quantity treated) $275 – $425
Prolotherapy – Sternoclavicular (each) $350
Platelet Rich Plasma (PRP)
Stem Cell Therapy (added to above cost of Prolotherapy) (amniotic / placental tissue) $1,500 – $2,700
Neural Therapy (depending on area treated) $150
Perineural injections / Neurofascial $150

Prolotherapy procedures are NOT billable to your health insurance.

How many treatments do I need?

It’s hard to say without an assessment, physical exam, and appropriate diagnostic imaging reports. However, typically 65-95% improvement is noticed with 4-8 Prolotherapy Treatments per joint or body region (i.e. – low back region) depending upon the severity of your condition. This is done over the course of 2-4 months.